Research Article | | Peer-Reviewed

Assessing the Safety and Efficacy of Spinal Anesthesia in Preterm and Term Neonates: A Multicenter Experience

Received: 20 May 2024     Accepted: 30 May 2024     Published: 14 June 2024
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Abstract

Background: Worldwide, the incidence of premature birth is increasing with its attending congenital anomalies, so complex surgical interventions to manage these congenital anomalies or complications are usually performed at early days of life. Neonates are vulnerable to apnea, and congenital cardiopulmonary problems and they have higher morbidity and mortality compared to older children and adults etc. In the preterm neonate, the risk of bronchopulmonary dysplasia and apnoea make their management complex and this is further compounded by their smaller size. Objective of study: The aim of the study was to determine the safety and efficacy of spinal anesthesia among neonates. Methodology: The study is a prospective study conducted in three tertiary health Institutions in northeast Nigeria. It includes all neonates scheduled for surgery amenable under SA. Sociodemographic variables, Haemodynamic variables, duration of surgery, and complications observed were all recorded. Results: Spinal anaesthesia SA was done in 230 patients, 90% of the patients were term, and only 10% were preterm. The majority were male with a mean weight of 3002 ± 660 grams and a mean age of 14.51±7.28 days. SA was successful in 93% of the patients in the first attempt. Heart rate, mean arterial pressure and oxygen saturation remained stable all through the duration of surgery. About 6% of the patients were converted to General Anaesthesia GA on account of prolonged surgery. The highest level of sympathetic block was recorded at the level of T4 while the lowest was at T6. Herniotomy was the most common surgery performed. The surgery lasted an average of 72 ± 28 minutes. No complication was recorded. Conclusion: Spinal anaesthesia provides a safe and reliable option for neonates who may require surgery early in life to improve their chances of survival. It serves as an alternative to GA with enhanced haemodynamic stability in this fragile population.

Published in International Journal of Anesthesia and Clinical Medicine (Volume 12, Issue 1)
DOI 10.11648/j.ijacm.20241201.19
Page(s) 47-52
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Spinal Anaesthesia, Preterm, Term Neonates, Haemodynamic Stability

References
[1] Whitaker EE, Wiemann BZ, DaJusta DG, Alpert SA, Ching CB, McLeod DJ, et al. Spinal anesthesia for pediatric urological surgery: reducing the theoretic neurotoxic effects of general anesthesia. Journal of pediatric urology. 2017; 13(4): 396-400.
[2] Williams RK, Adams DC, Aladjem EV, Kreutz JM, Sartorelli KH, Vane DW, et al. The safety and efficacy of spinal anesthesia for surgery in infants: the Vermont Infant Spinal Registry. Anesthesia & Analgesia. 2006; 102(1): 67-71.
[3] Subramaniam R. Anaesthetic concerns in preterm and term neonates. Indian Journal of Anaesthesia. 2019; 63(9): 771-9.
[4] Sola C, Hertz L, Bringuier S, De La Arena P, Macq C, Deziel-Malouin S, et al. Spinal anaesthesia in neonates and infants: what about the cerebral oxygen saturation? BJA: British Journal of Anaesthesia. 2017; 119(5): 964-71.
[5] Ciftci I, Apiliogullari S, Kara I, Gunduz E, Duman A. Repair of duodenal atresia under spinal anesthesia in a low-birth-weight preterm neonate: case report. Journal of Pediatric Surgery. 2012; 47(8): e33-e5.
[6] Randriamizao HM, Rakotondrainibe A, Razafindrabekoto LD, Ravoaviarivelo PF, Rajaonera AT, Andriamanarivo ML. Use of spinal anaesthesia in neonates and infants in Antananarivo, Madagascar: a retrospective descriptive study. BMC Research Notes. 2020; 13: 1-6.
[7] Ela AA, Ngayap G, Etoundi PO, Esiene A, Bengono R, Mikone A. La rachianesthésie chez l’enfant: bilan d’une année d’expérience à l’Hôpital Central de Yaoundé. Health Sciences and Disease. 2013; 14(4).
[8] Puncuh F, Lampugnani E, Kokki H. Use of spinal anaesthesia in paediatric patients: a single centre experience with 1132 cases. Pediatric anesthesia. 2004; 14(7): 564-7.
[9] Ecoffey C, Lacroix F, Giaufré E, Orliaguet G, Courrèges P, Française AdARPdE. Epidemiology and morbidity of regional anesthesia in children: a follow-up one-year prospective survey of the French-Language Society of Paediatric Anaesthesiologists (ADARPEF). Pediatric Anesthesia. 2010; 20(12): 1061-9.
[10] Kokki H. Spinal anaesthesia in infants and children. Best Practice & Research Clinical Anaesthesiology. 2000; 14(4): 687-707.
[11] Kachko L, Simhi E, Tzeitlin E, Efrat R, Tarabikin E, Peled E, et al. Spinal anesthesia in neonates and infants–a single-center experience of 505 cases. Pediatric Anesthesia. 2007; 17(7): 647-53.
[12] Dohms K, Hein M, Rossaint R, Coburn M, Stoppe C, Ehret CB, et al. Inguinal hernia repair in preterm neonates: is there evidence that spinal or general anaesthesia is the better option regarding intraoperative and postoperative complications? A systematic review and meta-analysis. BMJ open. 2019; 9(10): e028728.
[13] Lloyd JC, Wiener JS, Gargollo PC, Inman BA, Ross SS, Routh JC. Contemporary epidemiological trends in complex congenital genitourinary anomalies. The Journal of urology. 2013; 190(4): 1590-5.
[14] Shenkman Ze, Erez I, Freud E, Arnon S. Risk factors for spinal anesthesia in preterm infants undergoing inguinal hernia repair. Jornal de Pediatria. 2012; 88: 222-6.
[15] Disma N, Veyckemans F, Virag K, Hansen TG, Becke K, Harlet P, et al. Morbidity and mortality after anaesthesia in early life: results of the European prospective multicentre observational study, neonate and children audit of anaesthesia practice in Europe (NECTARINE). British journal of anaesthesia. 2021; 126(6): 1157-72.
[16] Frumiento C, Abajian JC, Vane DW. Spinal anesthesia for preterm infants undergoing inguinal hernia repair. Archives of Surgery. 2000; 135(4): 445-51.
[17] Jones LJ, Craven PD, Lakkundi A, Foster JP, Badawi N. Regional (spinal, epidural, caudal) versus general anaesthesia in preterm infants undergoing inguinal herniorrhaphy in early infancy. Cochrane database of systematic reviews. 2015(6).
[18] Tirmizi H. Spinal anesthesia in infants: recent developments. Current Opinion in Anesthesiology. 2015; 28(3): 333-8.
[19] Gerber AC, Weiss M. Awake spinal or caudal anaesthesia in preterms for herniotomies: what is the evidence based benefit compared with general anaesthesia? Current Opinion in Anesthesiology. 2003; 16(3): 315-20.
Cite This Article
  • APA Style

    Baffah, A. Y., Ballah, A. M., Bidemi, Y. H., Mohammed, J. M., Njidda, G. A., et al. (2024). Assessing the Safety and Efficacy of Spinal Anesthesia in Preterm and Term Neonates: A Multicenter Experience. International Journal of Anesthesia and Clinical Medicine, 12(1), 47-52. https://doi.org/10.11648/j.ijacm.20241201.19

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    ACS Style

    Baffah, A. Y.; Ballah, A. M.; Bidemi, Y. H.; Mohammed, J. M.; Njidda, G. A., et al. Assessing the Safety and Efficacy of Spinal Anesthesia in Preterm and Term Neonates: A Multicenter Experience. Int. J. Anesth. Clin. Med. 2024, 12(1), 47-52. doi: 10.11648/j.ijacm.20241201.19

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    AMA Style

    Baffah AY, Ballah AM, Bidemi YH, Mohammed JM, Njidda GA, et al. Assessing the Safety and Efficacy of Spinal Anesthesia in Preterm and Term Neonates: A Multicenter Experience. Int J Anesth Clin Med. 2024;12(1):47-52. doi: 10.11648/j.ijacm.20241201.19

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  • @article{10.11648/j.ijacm.20241201.19,
      author = {Adamu Yusuf Baffah and Abubakar Muhammad Ballah and Yahaya Halima Bidemi and Jika Mohammed Mohammed and Gyadale Abdulhamid Njidda and Nwokorie Rosemary Mabong and Galadima Hajara Aminu and Hassan Maina Ali and Ibrahim Naziru Joda and Abdullahi Muhammad Maryam and Adam Ibrahim Abdullahi and Andibanbang Franklin},
      title = {Assessing the Safety and Efficacy of Spinal Anesthesia in Preterm and Term Neonates: A Multicenter Experience
    },
      journal = {International Journal of Anesthesia and Clinical Medicine},
      volume = {12},
      number = {1},
      pages = {47-52},
      doi = {10.11648/j.ijacm.20241201.19},
      url = {https://doi.org/10.11648/j.ijacm.20241201.19},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijacm.20241201.19},
      abstract = {Background: Worldwide, the incidence of premature birth is increasing with its attending congenital anomalies, so complex surgical interventions to manage these congenital anomalies or complications are usually performed at early days of life. Neonates are vulnerable to apnea, and congenital cardiopulmonary problems and they have higher morbidity and mortality compared to older children and adults etc. In the preterm neonate, the risk of bronchopulmonary dysplasia and apnoea make their management complex and this is further compounded by their smaller size. Objective of study: The aim of the study was to determine the safety and efficacy of spinal anesthesia among neonates. Methodology: The study is a prospective study conducted in three tertiary health Institutions in northeast Nigeria. It includes all neonates scheduled for surgery amenable under SA. Sociodemographic variables, Haemodynamic variables, duration of surgery, and complications observed were all recorded. Results: Spinal anaesthesia SA was done in 230 patients, 90% of the patients were term, and only 10% were preterm. The majority were male with a mean weight of 3002 ± 660 grams and a mean age of 14.51±7.28 days. SA was successful in 93% of the patients in the first attempt. Heart rate, mean arterial pressure and oxygen saturation remained stable all through the duration of surgery. About 6% of the patients were converted to General Anaesthesia GA on account of prolonged surgery. The highest level of sympathetic block was recorded at the level of T4 while the lowest was at T6. Herniotomy was the most common surgery performed. The surgery lasted an average of 72 ± 28 minutes. No complication was recorded. Conclusion: Spinal anaesthesia provides a safe and reliable option for neonates who may require surgery early in life to improve their chances of survival. It serves as an alternative to GA with enhanced haemodynamic stability in this fragile population.
    },
     year = {2024}
    }
    

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  • TY  - JOUR
    T1  - Assessing the Safety and Efficacy of Spinal Anesthesia in Preterm and Term Neonates: A Multicenter Experience
    
    AU  - Adamu Yusuf Baffah
    AU  - Abubakar Muhammad Ballah
    AU  - Yahaya Halima Bidemi
    AU  - Jika Mohammed Mohammed
    AU  - Gyadale Abdulhamid Njidda
    AU  - Nwokorie Rosemary Mabong
    AU  - Galadima Hajara Aminu
    AU  - Hassan Maina Ali
    AU  - Ibrahim Naziru Joda
    AU  - Abdullahi Muhammad Maryam
    AU  - Adam Ibrahim Abdullahi
    AU  - Andibanbang Franklin
    Y1  - 2024/06/14
    PY  - 2024
    N1  - https://doi.org/10.11648/j.ijacm.20241201.19
    DO  - 10.11648/j.ijacm.20241201.19
    T2  - International Journal of Anesthesia and Clinical Medicine
    JF  - International Journal of Anesthesia and Clinical Medicine
    JO  - International Journal of Anesthesia and Clinical Medicine
    SP  - 47
    EP  - 52
    PB  - Science Publishing Group
    SN  - 2997-2698
    UR  - https://doi.org/10.11648/j.ijacm.20241201.19
    AB  - Background: Worldwide, the incidence of premature birth is increasing with its attending congenital anomalies, so complex surgical interventions to manage these congenital anomalies or complications are usually performed at early days of life. Neonates are vulnerable to apnea, and congenital cardiopulmonary problems and they have higher morbidity and mortality compared to older children and adults etc. In the preterm neonate, the risk of bronchopulmonary dysplasia and apnoea make their management complex and this is further compounded by their smaller size. Objective of study: The aim of the study was to determine the safety and efficacy of spinal anesthesia among neonates. Methodology: The study is a prospective study conducted in three tertiary health Institutions in northeast Nigeria. It includes all neonates scheduled for surgery amenable under SA. Sociodemographic variables, Haemodynamic variables, duration of surgery, and complications observed were all recorded. Results: Spinal anaesthesia SA was done in 230 patients, 90% of the patients were term, and only 10% were preterm. The majority were male with a mean weight of 3002 ± 660 grams and a mean age of 14.51±7.28 days. SA was successful in 93% of the patients in the first attempt. Heart rate, mean arterial pressure and oxygen saturation remained stable all through the duration of surgery. About 6% of the patients were converted to General Anaesthesia GA on account of prolonged surgery. The highest level of sympathetic block was recorded at the level of T4 while the lowest was at T6. Herniotomy was the most common surgery performed. The surgery lasted an average of 72 ± 28 minutes. No complication was recorded. Conclusion: Spinal anaesthesia provides a safe and reliable option for neonates who may require surgery early in life to improve their chances of survival. It serves as an alternative to GA with enhanced haemodynamic stability in this fragile population.
    
    VL  - 12
    IS  - 1
    ER  - 

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Author Information
  • Department of Anaesthesia and ICU, Federal Medical Center, Azare, Nigeria

  • Department of Anaesthesia and ICU, Abubakar Tafawa Balewa University, Bauchi, Nigeria

  • Department of Anaesthesia, Airdale NHS Foundation Trust, Steeton, UK

  • Department of Anaesthesia and ICU, Federal Teaching Hospital, Gombe, Nigeria

  • Department of Anaesthesia and ICU, Federal Teaching Hospital, Gombe, Nigeria

  • Department of Anaesthesia, Nile University Teaching Hospital, Abuja, Nigeria

  • Department of Anaesthesia and ICU, Federal Teaching Hospital, Gombe, Nigeria

  • Department of Anaesthesia and ICU, Modibbo Adama University Teaching Hospital, Yola, Nigeria

  • Department of Anaesthesia and ICU, Federal Teaching Hospital, Gombe, Nigeria

  • Department of Anaesthesia, South Qunfudah General Hospital, Makkah, Kingdom of Saudi Arabia

  • Department of Public Health, Bauchi State University, Bauchi, Nigeria

  • Department of Family Medicine, Fayfa hospital, Ministry of Health, Jazan, Saudi Arabia

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