International Journal of Anesthesia and Clinical Medicine

Volume 2, Issue 1, January 2014

  • A Mechanism for Inhaled Anesthetic-Induced Solid Organ Injury: Inflammation

    Gary E Hill, Irina Gasanova, Geoffrey M Thiele

    Issue: Volume 2, Issue 1, January 2014
    Pages: 1-7
    Received: 28 November 2013
    Published: 20 December 2013
    DOI: 10.11648/j.ja.20140201.11
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    Abstract: Background: Inhaled anesthetics, including halothane, iso- and sevoflurane induce proinflammatory cytokine release. Halothane is an inhaled anesthetic agent that is metabolized by the liver into a highly reactive product, trifluoroacetyl chloride, which can react endogenously to form a trifluoroacetyl-adduct (TFA-adduct). The MAA-adduct is formed b... Show More
  • Is Asthma still a Risk Factor for General Anesthesia

    Ji Li, Ross Mac Pherson

    Issue: Volume 2, Issue 1, January 2014
    Pages: 8-12
    Received: 6 January 2014
    Published: 30 March 2014
    DOI: 10.11648/j.ja.20140201.12
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    Abstract: Objective: To assess the incidence of anaesthetic complications in a cohort of patients with asthma undergoing anaesthesia and surgery. Design, Setting and Patients: 79 patients (who underwent a total of 80 anaesthetics) who were admitted for elective surgery at a major tertiary referral hospital, during a seven month period were enrolled. Data on ... Show More