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Intraoperative Hypoxemia in the Right Lateral Decubitus Position: A Case Report

Received: 28 March 2024     Accepted: 11 April 2024     Published: 28 April 2024
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Abstract

Platypnea-Orthodeoxia syndrome (POS), an exceptionally uncommon condition, is characterized by decreased oxygen saturation in an upright posture with corresponding improvement in the supine position. Recently, an 85-year-old female patient presented for surgery due to a left femoral neck fracture. Following successful tracheal intubation and anesthesia induction, the ventilator indicated an airway pressure of 15mmHg. While in the right lateral decubitus position, the patient developed hypoxia despite normal arterial blood pressure and symmetrical breath sounds. Attempts to alleviate the hypoxia through pure oxygen ventilation, tympanic lung ventilation, and high-frequency ventilation were unsuccessful. Subsequently, there was a notable decrease in both blood pressure and heart rate, prompting an immediate halt to the surgery and repositioning the patient to the supine position. This resulted in the normalization of the patient's heart rate, oxygen saturation, and blood pressure. To investigate the etiology, a TEE probe was inserted, revealing the presence of a patent foramen ovale (PFO) and a significant right-to-left shunt while the patient was in the lateral position. The procedure was performed in a specific right lateral decubitus position. This case may represent a unique manifestation of POS syndrome, expanding the differential diagnosis for intraoperative position-related hypoxemia. Given the severe hypoxemia observed with intraoperative positional changes, a strong suspicion of POS syndrome is warranted.

Published in International Journal of Anesthesia and Clinical Medicine (Volume 12, Issue 1)
DOI 10.11648/j.ijacm.20241201.17
Page(s) 33-37
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Platypnea-Orthodeoxia, Intraoperative Hypoxemia, Right Lateral Position, Artificial Femoral Head Replacement, Patent Foramen Ovale, Transesophageal Echocardiography

References
[1] Shiraishi Y, Hakuno D, et al. Platypnea-orthodeoxia syndrome due to PFO and aortic dilation. JACC Cardiovasc Imaging. 2012; 5(5): 570-571.
[2] Verdoia M, Viola O, et. al. Managing Congenital Heart Defects in Elderly: The Platypnea-Orthodeoxia Syndrome in Underestimated Patent Foramen Ovale. Angiology. 2023 Aug 31: 33197231199229.
[3] Sitbon S, Ou P, Nguyen C, et. al. Four-Dimensional Flow Magnetic Resonance Imaging Features of a Platypnea-Orthodeoxia Syndrome Caused by a Patent Foramen Ovale. Circ Cardiovasc Imaging. 2023 Jul; 16(7): 601-603.
[4] Cutsforth-Gregory JK, Benarroch EE, et. al. Platypnea-orthodeoxia syndrome mimicking postural orthostatic tachycardia syndrome. Clin Auton Res. 2021 Aug; 31(4): 573-576.
[5] Hashimoto M, Okawa Y, et al. Platypnea-orthodeoxia syndrome combined with constrictive pericarditis after coronary artery bypass surgery. J Thorac Cardiovasc Surg. 2006; 132(5): 1225-1226.
[6] Ribeiro R, Fialho I, et. al. Platypnea-Orthodeoxia Syndrome: A Case of Persistent Hypoxemia in an Elderly Patient. Circulation. 2021 Aug 3; 144(5): 395-398.
[7] Kass M, Grocott HP, et al. Constellation of Stroke, Pulmonary Embolism, and Platypnea Orthodeoxia Syndrome: The Elusive Patent Foramen Ovale. JACC Cardiovasc Interv. 2021 Jul 26; 14(14): e165-e167.
[8] Koutroulou I, Tsivgoulis G, et al. Epidemiology of Patent Foramen Ovale in General Population and in Stroke Patients: A Narrative Review. Front Neurol. 2020 Apr 28; 11: 281.
[9] Othman F, Bailey B, et al. Platypnea-Orthodeoxia Syndrome in the Setting of Patent Foramen Ovale Without Pulmonary Hypertension or Major Lung Disease. J Am Heart Assoc. 2022 Aug 2; 11(15): e024609.
[10] Agrawal A, Palkar A, et al. The multiple dimensions of Platypnea-Orthodeoxia syndrome: A review. Respir Med. 2017; 129: 31-38.
[11] Jung SY, Kim NK, et. al. Transcatheter treatment of atrial septal defect presenting with platypnea-orthodeoxia syndrome. Korean Circ J. 2015 Mar; 4 5(2): 169-73.
[12] Neuvillers L, Masri A, et al. Platypnea-orthodeoxia syndrome: comprehensive analysis by multimodal imaging. Eur Heart J. 2021 Oct 7; 42(38): 3995.
[13] Zhou J, He J, et al. Case report: Unusual cause of refractory hypoxemia after pacemaker lead extraction. Front Cardiovasc Med. 2023 Aug 14; 10: 1237595.
[14] Ng KJ, Li YD. Cardiac platypnea-orthodeoxia syndrome in a 73-year-old woman. CMAJ. 2015; 187(18): 1385-1388.
[15] Shah AH, Osten M, et al. Percutaneous intervention to treat platypnea-orthodeoxia syndrome: the Toronto Experience. JACC Cardiovasc Interv. 2016; 9: 1928–1938.
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  • APA Style

    Wu, G., Xu, H. (2024). Intraoperative Hypoxemia in the Right Lateral Decubitus Position: A Case Report. International Journal of Anesthesia and Clinical Medicine, 12(1), 33-37. https://doi.org/10.11648/j.ijacm.20241201.17

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    ACS Style

    Wu, G.; Xu, H. Intraoperative Hypoxemia in the Right Lateral Decubitus Position: A Case Report. Int. J. Anesth. Clin. Med. 2024, 12(1), 33-37. doi: 10.11648/j.ijacm.20241201.17

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    AMA Style

    Wu G, Xu H. Intraoperative Hypoxemia in the Right Lateral Decubitus Position: A Case Report. Int J Anesth Clin Med. 2024;12(1):33-37. doi: 10.11648/j.ijacm.20241201.17

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  • @article{10.11648/j.ijacm.20241201.17,
      author = {Guowei Wu and Hongwei Xu},
      title = {Intraoperative Hypoxemia in the Right Lateral Decubitus Position: A Case Report
    },
      journal = {International Journal of Anesthesia and Clinical Medicine},
      volume = {12},
      number = {1},
      pages = {33-37},
      doi = {10.11648/j.ijacm.20241201.17},
      url = {https://doi.org/10.11648/j.ijacm.20241201.17},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijacm.20241201.17},
      abstract = {Platypnea-Orthodeoxia syndrome (POS), an exceptionally uncommon condition, is characterized by decreased oxygen saturation in an upright posture with corresponding improvement in the supine position. Recently, an 85-year-old female patient presented for surgery due to a left femoral neck fracture. Following successful tracheal intubation and anesthesia induction, the ventilator indicated an airway pressure of 15mmHg. While in the right lateral decubitus position, the patient developed hypoxia despite normal arterial blood pressure and symmetrical breath sounds. Attempts to alleviate the hypoxia through pure oxygen ventilation, tympanic lung ventilation, and high-frequency ventilation were unsuccessful. Subsequently, there was a notable decrease in both blood pressure and heart rate, prompting an immediate halt to the surgery and repositioning the patient to the supine position. This resulted in the normalization of the patient's heart rate, oxygen saturation, and blood pressure. To investigate the etiology, a TEE probe was inserted, revealing the presence of a patent foramen ovale (PFO) and a significant right-to-left shunt while the patient was in the lateral position. The procedure was performed in a specific right lateral decubitus position. This case may represent a unique manifestation of POS syndrome, expanding the differential diagnosis for intraoperative position-related hypoxemia. Given the severe hypoxemia observed with intraoperative positional changes, a strong suspicion of POS syndrome is warranted.
    },
     year = {2024}
    }
    

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    AB  - Platypnea-Orthodeoxia syndrome (POS), an exceptionally uncommon condition, is characterized by decreased oxygen saturation in an upright posture with corresponding improvement in the supine position. Recently, an 85-year-old female patient presented for surgery due to a left femoral neck fracture. Following successful tracheal intubation and anesthesia induction, the ventilator indicated an airway pressure of 15mmHg. While in the right lateral decubitus position, the patient developed hypoxia despite normal arterial blood pressure and symmetrical breath sounds. Attempts to alleviate the hypoxia through pure oxygen ventilation, tympanic lung ventilation, and high-frequency ventilation were unsuccessful. Subsequently, there was a notable decrease in both blood pressure and heart rate, prompting an immediate halt to the surgery and repositioning the patient to the supine position. This resulted in the normalization of the patient's heart rate, oxygen saturation, and blood pressure. To investigate the etiology, a TEE probe was inserted, revealing the presence of a patent foramen ovale (PFO) and a significant right-to-left shunt while the patient was in the lateral position. The procedure was performed in a specific right lateral decubitus position. This case may represent a unique manifestation of POS syndrome, expanding the differential diagnosis for intraoperative position-related hypoxemia. Given the severe hypoxemia observed with intraoperative positional changes, a strong suspicion of POS syndrome is warranted.
    
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